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I have been looking into Copper and its know mutagenic properties. Several studies have linked cancer with high Copper levels. Research also shows that the copper transport plays a role in MDR, multi drug resistant cancers and can lower the efficacy of chemotherapy. The cellular ATP7A and ATP7B related drug transport system is thought to play a role in chemo sensitivity. It has been shown that patients with high Copper levels are more resistant to Chemotherapy.

It has also been shown that many cancer patients have high copper levels compared to people with no cancer. With high Copper, you can also expect low Zinc levels as Copper displaces Zinc.

One question that I have not been able to find an answer to is, “Why do cancer patients tend to have high Copper levels?”. Is it a symptom of the disease, or does cancer arise more often in individuals with high Copper levels? (If anyone knows the answer please post a comment).

With all the above in mind, it was time to test my Copper and Zinc levels. It came as no great surprise to discover that I had Copper levels well above the normal range, and Zinc levels below normal.

There is research and some clinical trials running to investigate Copper Chelation as a cancer treatment. The theory is that low Copper levels retard the growth of cancer, and at the same time make chemotherapy more effective.

The most common agent used for copper chelation is tetrathiomolybdate. I have this on order and will start with Copper chelation as soon as it arrives. Chelation agents will bind to heavy metals like Copper, and remove it from the body. Care should be taken, as Copper is an essential element. You want to achieve low copper levels, but not too low. Zinc should also be monitored as too much zinc can be toxic as well.

A cheaper alternative to tetrathiomolybdate is N-Acetyl-L-Cysteine (NAC). This is available in most health stores. NAC is however less effective and takes longer compared to tetrathiomolybdate.

My next step is to get other family members tested for Copper. If they also show high Copper levels, the first thing I will do, is get my old Copper plumbing replaced. I have also stopped taking a multivitamin as it contains Copper.

It took a while, but my Tetrathiomolybdate order arrived today. TTM is a powerful copper chelator and because I have high copper levels and the fact that copper is crucial to angiogenesis, its time to get as much copper out of my body.

Tetrathiomolybdate (TTM) was developed as an effective anticopper therapy for the treatment of Wilson’s disease, a disorder that leads to abnormal copper accumulation. As copper plays an important role in angiogenesis it is speculated that copper depletion can lead to stable disease in metastatic cancer. This outcome has in fact been observed in several clinical studies.

Resources

1. Treatment of Metastatic Cancer with Tetrathiomolybdate, an Anticopper, Antiangiogenic Agent: Phase I Study
2. Phase II Study of Tetrathiomolybdate (TM) in Patients With Breast Cancer
3. The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies
4. A pilot trial of the anti-angiogenic copper lowering agent tetrathiomolybdate in combination with irinotecan, 5-flurouracil, and leucovorin for metastatic colorectal cancer.

The qigong master that I have been seeing for the last few months has recommended that I go on a ten day dry fast. That’s ten days without food or water. At first glance it sounds insane as it is documented that people tend to die from dehydration after 3-5 days without water, however there are many cases of people surviving a 10-14 day dry fast when not exposed to harsh elements of an outdoor survival situation.

I understand the concept of dry fasting. The lack of food depletes glucose storage and the lack of water increases detox and forces the body into a ketogenic state sooner as the body needs to digest fats to help replenish water stores. It is said that a ten day dry fast is equivalent to a 30 day water fast. I can’t afford to lose too much body weight, so a ten day dry fast sounds like the better option. I still have my doubts, but I have decided to try it and to see how far I get. My qigong master is adamant that this will cure me of my cancer. He quoted numerous examples of past cancer patients he treated all with great results apparently. Well I’ll believe that when I see my next CT scans, but I have decided to give it a go as this may be the only chance to do so while I am still in relatively good health. The risks however include the decimation of my ‘relatively good health’.

A body that is going through a dry fast will dehydrate slowly and the whole body will drastically slow down resulting in a minimal need for water. The body’s water level can however fall dangerously low and this may result in organ failure, even death.

Dry fast completely cleanses the excretory system and removes metabolic waste and toxins from the body. During a dry fast, the body’s digestive system does not need to function as it is not receiving any nourishment. With the reduced workload, the immune system is able to function better too.

While some people dry fast for as many as 10 or 14 days, it is usually recommended to try this fast for just three to five days. (I decided to try for the whole 10 days as I may not get another chance.)

While dry fasting, you should not perform any strenuous activities. This includes sex. Sunlight exposure should also be minimized. Light activity is recommended as this can help the body to detox. Rest or meditate when feeling weak.

Imagining yourself eating a full meal and going through the motions of eating and swallowing can alleviate the feelings of hunger and thirst. Ideally you should try to eat 3 or more virtual meals a day. (I have a good imagination, so intend to pig out.)

My biggest fear is that my qigong master could be right. If my little mutants start to commit suicide (apoptosis) on mass, as result of the dry fast conditions, I will be in trouble. I have somewhere between 1.5 and 2 kilograms of tumour mass. If the cancer cells die too quickly, the resulting toxic shock could be too much for the kidneys to handle.

I will start on the dry fast next week, once the current round of chemo drugs leave my body. I’ll write up a day by day account of this experiment and will follow up with a CEA blood test and possibly a new CT scan, so stay tuned…

I should add that this is way out of my comfort zone, and not something I would even contemplate under normal circumstances, but having pretty much failed both first and second line chemo in just 5 months, my treatment options are dwindling. A lot of anecdotal evidence exists for potential cures after extended fasts so I figure its worth the risk. I also love a good challenge, and this should be as good as it gets.

Apparently coffee enemas are all the rage these days, so it was time that I too got onto the bandwagon. (I am going to spare you the details and if you need detailed instruction, just google them.) Had my third today, all in preparation for my 10 day dry fast. The aim is to detox my liver as much as possible.

How Does it Work?

The last part of the large intestine is called the sigmoid colon. By the time fecal matter arrives here, its mostly devoid of nutrients, but contains numerous toxins resulting from putrefaction. A special circulatory system (enterohroatic circulation) exits here and its purpose is to deliver sigmoidal toxins directly to the liver for processing. This is the pathway that Caffeine and other chemicals contained in coffee use to pass directly to the liver, bypassing the main circulatory system in the process. This in turn stimulates detoxification and releases accumulated toxins through bile excretion. Endoscopic studies have confirmed that following a coffee enema, bile output is significantly increased within just a few minutes following its application.

Once bile production is stimulated, stored toxins are eliminated and this frees the liver to process more toxins from the bloodstream. The bile is released into the small intestine. This results in additional benefits including the alkalinization of the small intestine and improved digestion.

In addition to Caffeine, coffee also contains alkaloids which stimulate the production of the enzyme glutathione-S-transferase. This enzyme is crucial to the proper function of the liver detox pathways. The production of this enzyme speeds up the rate of detoxification.

The secondary benefit is the colon cleansing itself. Coffee acts as an astringent, helping to clean the colon walls.

Coffee enemas were pioneered in Germany by Dr. Gerson. For cancer patients, Dr. Gerson recommended up to 6 enemas per day. Extended use by his patients did not appear to result in serious side-effects. I personally think that one a day is enough.

Side Effects

Mainstream Oncologists typically do not recommend enemas during chemotherapy as it is believed to increase the chance of bowel perforation.

Other potential side effects include: infections, sepsis, severe electrolyte imbalance, colitis, proctocolitis, salmonella, brain abscess, and heart failure. Long term use of coffee enemas can also lead to malabsorption of fat, fat-soluble vitamins, and calcium.